SCHEMBL17265384

SCHEMBL17265384

c1ccc2cc(-c3ccc4c(c3)Oc3cccc5c3c-4cc3c4ccccc4c(-c4cccc6ccccc46)cc53)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ATM Q13315 2/20 0.40
PIM1 P11309 3/20 0.38
ALDH1A1 P00352 4/20 0.35
MAPT P10636 1/20 0.35
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA9 Q16790 3/20 0.34
HSD17B10 Q99714 3/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
HIF1A Q16665 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
CYP1A2 P05177 2/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17265400 0.92 KDM4E (0.36) MAPK1KDM4EATMPIM1ALDH1A1
SCHEMBL19600406 0.90 MAPK1 (0.47) MAPK1KDM4EATMPIM1ALDH1A1
SCHEMBL17265386 0.90 CA12 (0.38) MAPK1KDM4EATMPIM1ALDH1A1
SCHEMBL17265392 0.88 KDM4E (0.37) MAPK1KDM4EATMALDH1A1CA1
SCHEMBL17265380 0.88 MAPK1 (0.36) MAPK1KDM4EATMPIM1ALDH1A1
SCHEMBL17265414 0.85 GPR84 (0.39) MAPK1KDM4EATMALDH1A1HSD17B10
SCHEMBL17120202 0.84 PIM1 (0.39) MAPK1KDM4EATMPIM1ALDH1A1
SCHEMBL17265406 0.83 CYP1A2 (0.38) MAPK1KDM4EATMALDH1A1HSD17B10
SCHEMBL19600428 0.83 MAPK1 (0.40) MAPK1KDM4EATMPIM1ALDH1A1
SCHEMBL19600435 0.83 MAPK1 (0.40) MAPK1KDM4EATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed