SCHEMBL19600428

SCHEMBL19600428

c1ccc2cc(-c3ccc4c5c(cccc35)Oc3cc(-c5cc6c7ccccc7ccc6c6ccccc56)ccc3-4)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ATM Q13315 1/20 0.40
GSTP1 P09211 1/20 0.35
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
HPRT1 P00492 4/20 0.34
GPR84 Q9NQS5 1/20 0.33
ALDH1A1 P00352 3/20 0.31
CYP1A2 P05177 3/20 0.31
HPGD P15428 2/20 0.31
HIF1A Q16665 2/20 0.31
ERBB2 P04626 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17120235 0.88 CA1 (0.37) MAPK1KDM4EATMALDH1A1HPGD
SCHEMBL19600419 0.87 GPR84 (0.36) MAPK1KDM4EATMHPRT1GPR84
SCHEMBL17120197 0.86 KDM4E (0.36) MAPK1KDM4EATMALDH1A1PIM1
SCHEMBL19600435 0.85 MAPK1 (0.40) MAPK1KDM4EATMCYP1A1CYP1B1
SCHEMBL17167452 0.85 MAPK1 (0.47) MAPK1KDM4EATMGSTP1CYP1A1
SCHEMBL17265392 0.85 KDM4E (0.37) MAPK1KDM4EATMGSTP1GPR84
SCHEMBL19600430 0.85 KDM4E (0.45) MAPK1KDM4EATMGSTP1GPR84
SCHEMBL15856985 0.85 MAPK1 (0.49) MAPK1KDM4EATMGSTP1CYP1A1
SCHEMBL17265386 0.85 CA12 (0.38) MAPK1KDM4EATMCYP1A1GPR84
SCHEMBL19600406 0.85 MAPK1 (0.47) MAPK1KDM4EATMGSTP1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 MAPK1 2174/4885KDM4E 2074/4885ATM 2475/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 MAPK1 2174/4885KDM4E 2074/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.