Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839412 | 1.00 | PPARA (0.61) | PPARAALBPLA2G4BL3MBTL1HDAC1 | |
| Hydrochloric Acid SCHEMBL830247 | 0.98 | PPARA (0.59) | PPARAALBPLA2G4BL3MBTL1HDAC1 | |
| SCHEMBL16245586 | 0.98 | PPARA (0.63) | PPARAALBPLA2G4BL3MBTL1HDAC1 | |
| SCHEMBL12099337 | 0.93 | PPARA (0.56) | PPARAALBPLA2G4BL3MBTL1FFAR1 | |
| SCHEMBL31448424 | 0.91 | PPARA (0.71) | PPARAALBPLA2G4BL3MBTL1HDAC1 | |
| SCHEMBL21073528 | 0.91 | PPARA (0.71) | PPARAALBPLA2G4BL3MBTL1HDAC1 | |
| SCHEMBL29141429 | 0.91 | PPARA (0.71) | PPARAALBPLA2G4BL3MBTL1HDAC1 | |
| SCHEMBL31448470 | 0.89 | PPARA (0.73) | PPARAALBPLA2G4BL3MBTL1HDAC1 | |
| SCHEMBL2198008 | 0.87 | L3MBTL1 (0.67) | PPARAL3MBTL1FFAR1 | |
| Hydrochloric Acid SCHEMBL25375206 | 0.85 | L3MBTL1 (0.65) | PPARAL3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015175813-A1 | HETEROCYCLIC HYDROXAMIC ACIDS AS PROTEIN DEACETYLASE INHIBITORS AND DUAL PROTEIN DEACETYLASE-PROTEIN KINASE INHIBITORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-11-19 | — | — | WO | disclosed |