SCHEMBL2198008

SCHEMBL2198008

Nc1ccc(OCCC(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.67
MMP2 P08253 1/20 0.57
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
FFAR1 O14842 3/20 0.50
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.50
PPARA Q07869 2/20 0.49
TDP1 Q9NUW8 2/20 0.48
MCL1 Q07820 1/20 0.47
LTA4H P09960 1/20 0.46
PARP10 Q53GL7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25375206 0.98 L3MBTL1 (0.65) L3MBTL1MMP2NPC1RAB9AFFAR1
SCHEMBL38747 0.91 PPARA (0.62) L3MBTL1MMP2NPC1RAB9AFFAR1
SCHEMBL12099337 0.90 PPARA (0.56) L3MBTL1NPC1RAB9AFFAR1LMNA
SCHEMBL16245586 0.89 PPARA (0.63) L3MBTL1NPC1RAB9AFFAR1PPARA
SCHEMBL17265696 0.87 PPARA (0.61) L3MBTL1FFAR1PPARA
SCHEMBL839412 0.87 PPARA (0.61) L3MBTL1FFAR1PPARA
Hydrochloric Acid SCHEMBL830247 0.85 PPARA (0.59) L3MBTL1FFAR1PPARA
SCHEMBL11288854 0.85 L3MBTL1 (0.50) L3MBTL1MMP2NPC1RAB9AFFAR1
SCHEMBL5191886 0.82 TDP1 (0.52) L3MBTL1NPC1RAB9ATSHRTDP1
SCHEMBL4842616 0.82 FFAR1 (0.61) L3MBTL1MMP2FFAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112062671-B Preparation method of R- (+) -2- (4-hydroxyphenoxy) propionic acid 苏州开元民生科技股份有限公司 2021-02-09 CN claimed
CN-112062671-A Preparation method of R- (+) -2- (4-hydroxyphenoxy) propionic acid 苏州开元民生科技股份有限公司 2020-12-11 CN claimed
US-4064129-A Process for making quinacridone and its derivatives HARMON COLORS CORPORATION (US) 1977-12-20 US claimed
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof LIU, MIAO (CN) 2023-08-10 US disclosed
CN-112062671-B Preparation method of R- (+) -2- (4-hydroxyphenoxy) propionic acid 苏州开元民生科技股份有限公司 2021-02-09 CN disclosed
CN-112062671-A Preparation method of R- (+) -2- (4-hydroxyphenoxy) propionic acid 苏州开元民生科技股份有限公司 2020-12-11 CN disclosed
EP-2864289-B1 CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS CB THERAPEUTICS INC (KY) 2018-04-11 EP disclosed
EP-1246792-B1 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECH INC (US) 2014-08-13 EP disclosed
US-7977506-B2 Amino acid for delivering active materials; bioavailability EMISPHERE TECHNOLOGIES, INC. (US) 2011-07-12 US disclosed
WO-2009117515-A2 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS AURIMMED PHARMA, INC. (US) 2009-09-24 WO disclosed
WO-2008031034-A2 THERAPEUTIC COMPOUNDS FOR DISEASES AND DISORDERS MYRIAD GENETICS, INC. (US) 2008-03-13 WO disclosed
US-7151191-B2 Compounds and compositions for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2006-12-19 US disclosed
EP-1246792-A4 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECH INC (US) 2005-02-16 EP disclosed
US-20030149296-A1 Compounds and compositions for delivering active agents NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2003-08-07 US disclosed
EP-1246792-A1 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS Emisphere Technologies, Inc. (US) 2002-10-09 EP disclosed
WO-2001051454-A1 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2001-07-19 WO disclosed
EP-0211326-B1 PRODUCTION OF GRAVURE INKS FOR ILLUSTRATIONS BAYER AG (DE) 1990-06-06 EP disclosed
US-4739042-A ESTERIFICATION OF AN HYDROXY PYRIDONE DYESTUFF WITH CARBOXYLIC PYRIDINE DYESTUFF BAYER AKTIENGESELLSCHAFT (DE) 1988-04-19 US disclosed
EP-0211325-A2 Method of making heliographic and flexographic printing inks BAYER AG (DE) 1987-02-25 EP disclosed
EP-0211326-A2 Production of gravure inks for illustrations BAYER AG (DE) 1987-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149296-A1 Compounds and compositions for delivering active agents SERPINB1, ELANE, MMP8 L3MBTL1 3798/4885MMP2 162/4885NPC1 52/4885
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof VIP, GHITM, MYCBP L3MBTL1 2113/4885MMP2 533/4885NPC1 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.