Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25588047 | 1.00 | MEN1 (0.61) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL22961020 | 0.90 | MEN1 (0.58) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL19865693 | 0.86 | L3MBTL1 (0.57) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL20353277 | 0.81 | TAS1R3 (0.49) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL25588081 | 0.81 | MEN1 (0.56) | MEN1KMT2AL3MBTL1CASRALDH1A1 | |
| SCHEMBL11824647 | 0.81 | BCHE (0.74) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL696773 | 0.81 | MEN1 (0.58) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL3508651 | 0.81 | MEN1 (0.58) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL20502219 | 0.81 | L3MBTL1 (0.56) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10263818 | 0.81 | L3MBTL1 (0.56) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |