Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24274248 | 0.84 | MTNR1A (0.39) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL1830924 | 0.76 | — | — | |
| SCHEMBL4957302 | 0.76 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL983886 | 0.75 | — | — | |
| SCHEMBL10311744 | 0.75 | — | — | |
| SCHEMBL10311755 | 0.75 | — | — | |
| SCHEMBL19492608 | 0.73 | MTNR1A (0.42) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL10840027 | 0.72 | MTNR1A (0.35) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL1866035 | 0.72 | KDM4E (0.43) | MTNR1AMTNR1BKDM4EMAPK1HIF1A | |
| SCHEMBL10062233 | 0.72 | MTNR1A (0.44) | MTNR1AMTNR1BKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015175845-A1 | BENZIMIDAZOLE DERIVATIVES AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2015-11-19 | — | — | WO | disclosed |