SCHEMBL4957302

SCHEMBL4957302

CC(=O)NCC(C)NC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 12/20 0.40
MTNR1B P49286 12/20 0.40
ALDH1A1 P00352 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
NFKB1 P19838 1/20 0.37
PTGS2 P35354 1/20 0.37
THPO P40225 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ACACB O00763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9366857 0.84 MTNR1A (0.38) MTNR1AMTNR1BALDH1A1KDM4EMAPK1
SCHEMBL23223590 0.84 MTNR1A (0.37) MTNR1AMTNR1BALDH1A1KDM4EMAPK1
SCHEMBL5010901 0.83 MTNR1A (0.32) MTNR1AMTNR1BALDH1A1ACACB
SCHEMBL20694108 0.82 MTNR1A (0.36) MTNR1AMTNR1BALDH1A1KDM4EMAPK1
SCHEMBL23223577 0.82 MTNR1A (0.36) MTNR1AMTNR1BALDH1A1KDM4EMAPK1
SCHEMBL20693686 0.82 MTNR1A (0.36) MTNR1AMTNR1BALDH1A1KDM4EMAPK1
SCHEMBL14559398 0.81 DPP4 (0.44) MTNR1AMTNR1BKDM4EMAPK1HIF1A
SCHEMBL15671916 0.80
SCHEMBL12583410 0.80
SCHEMBL1830924 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3781661-B1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-13 EP disclosed
US-11525106-B2 Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-13 US disclosed
CN-112400014-B Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators 陶氏环球技术有限责任公司 2022-10-25 CN disclosed
US-20210155877-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC 2021-05-27 US disclosed
EP-3781661-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS Dow Global Technologies, LLC (US) 2021-02-24 EP disclosed
WO-2019204184-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-24 WO disclosed
WO-2019204184-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-24 WO disclosed
US-20120123065-A1 Hydrolytically Stable Maleimide-Terminated Polymers NEKTAR THERAPEUTICS (US) 2012-05-17 US disclosed
US-8106131-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS (US) 2012-01-31 US disclosed
US-20090012241-A1 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-01-08 US disclosed
US-7432331-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-10-07 US disclosed
EP-1018536-A1 LUMINESCENT PLASTIC MATERIAL AND PROCESS FOR PRODUCING THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-12 EP disclosed
EP-0927745-A1 OPTICAL PLASTIC MATERIAL AND PROCESS FOR THE PRODUCTION THEREOF KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11525106-B2 Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators AADAC, DLAT, NAT10 MTNR1A 3848/4885MTNR1B 3876/4885ALDH1A1 1218/4885
US-20210155877-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS AADAC, DLAT, NAT10 MTNR1A 3848/4885MTNR1B 3876/4885ALDH1A1 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.