Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046811 | 0.91 | GAA (0.49) | ALDH1A1GAASMN1; SMN2SLC9A1RAB9A | |
| SCHEMBL12204565 | 0.90 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2SLC9A1RAB9AKEAP1 | |
| SCHEMBL15632082 | 0.85 | SMN1; SMN2 (0.57) | ALDH1A1GAASMN1; SMN2SLC9A1RAB9A | |
| SCHEMBL165333 | 0.84 | SMN1; SMN2 (0.71) | ALDH1A1GAASMN1; SMN2SLC9A1RAB9A | |
| SCHEMBL25008763 | 0.82 | SMN1; SMN2 (0.48) | ALDH1A1GAASMN1; SMN2SLC9A1RAB9A | |
| SCHEMBL16614107 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1GAASMN1; SMN2SLC9A1RAB9A | |
| SCHEMBL4799345 | 0.81 | NPC1 (0.65) | ALDH1A1SMN1; SMN2SLC9A1RAB9AKEAP1 | |
| SCHEMBL503004 | 0.81 | KCNMA1 (0.59) | ALDH1A1SMN1; SMN2SLC9A1RAB9AKEAP1 | |
| SCHEMBL10069688 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2SLC9A1RAB9AKEAP1 | |
| SCHEMBL3977744 | 0.81 | TDP1 (0.56) | ALDH1A1GAASMN1; SMN2SLC9A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298616-A | Composition for forming photosensitive insulating film | 日产化学株式会社 | 2022-11-04 | — | — | CN | disclosed |
| EP-4006035-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Neupharma, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-3831836-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3421467-A1 | 5-PHENYLAZAINDOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT | Shionogi & Co., Ltd (JP) | 2019-01-02 | — | — | EP | disclosed |
| WO-2018129556-A1 | COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | ARDELYX, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| EP-1742635-B1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC (US) | 2018-03-07 | — | — | EP | disclosed |
| WO-2017117006-A1 | USE OF A DHODH INHIBITOR IN COMBINATION WITH AN INHIBITOR OF PYRIMIDINE SALVAGE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-07-06 | — | — | WO | disclosed |
| EP-2909192-B1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-17 | — | — | EP | disclosed |
| EP-2428504-B1 | Small molecule inhibitors of the pleckstrin homology domain and method for using same | UNIV TEXAS (US) | 2017-05-17 | — | — | EP | disclosed |
| US-9340549-B2 | Oxazolidinone compounds and derivatives thereof | AMGEN INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | AMGEN INC. | 2015-02-12 | — | — | US | disclosed |
| EP-1827678-B1 | METHOD AND APPARATUS FOR PERFORMING MICRO-SCALE CHEMICAL REACTIONS | TOTAL SYNTHESIS LTD (CA) | 2012-07-18 | — | — | EP | disclosed |
| EP-1521125-B1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-1002828-A2 | Transparent construction sheet | Petglass, S.L. (ES) | 2000-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | TNKS1BP1, TNKS, TBKBP1 | ALDH1A1 1646/4885GAA 264/4885SMN1; SMN2 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.