Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958353 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL409599 | 0.96 | — | — | |
| SCHEMBL10962997 | 0.92 | TSHR (0.43) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL11082402 | 0.89 | — | — | |
| SCHEMBL20579108 | 0.85 | MEN1 (0.45) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL20578805 | 0.85 | CA1 (0.32) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL19879952 | 0.85 | CA1 (0.37) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL9817124 | 0.85 | TSHR (0.34) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL9817087 | 0.85 | TSHR (0.34) | TSHRALDH1A1TDP1CA1CA2 | |
| SCHEMBL28726457 | 0.85 | MEN1 (0.61) | TSHRALDH1A1TDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034613-A3 | REFRIGERATOR | RED BULL GMBH (AT) | 2012-05-10 | — | — | WO | disclosed |
| EP-1329513-B1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIV WASHINGTON (US) | 2011-12-07 | — | — | EP | disclosed |
| US-7544518-B2 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2009-06-09 | — | — | US | disclosed |
| US-6852544-B2 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2005-02-08 | — | — | US | disclosed |
| US-6670194-B1 | Mass spectrometry; screening for changes in the expression of enzymatic activity of specific proteins induced by absence, deficiency or excess of a given protein | UNIVERSITY OF WASHINGTON | 2003-12-30 | — | — | US | disclosed |
| EP-1105517-B1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIV WASHINGTON (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-1329513-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2003-05-08 | — | — | US | disclosed |
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TSHR 1779/4885ALDH1A1 4601/4885TDP1 4040/4885 |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TSHR 1779/4885ALDH1A1 4601/4885TDP1 4040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.