Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817087 | 1.00 | TSHR (0.34) | TSHRCYP3A4CA2CA1TDP1 | |
| SCHEMBL17070883 | 0.90 | MEN1 (0.38) | TSHRCYP3A4CA2ALDH1A1MEN1 | |
| SCHEMBL8704616 | 0.90 | CA1 (0.30) | CA2CA1 | |
| SCHEMBL25921552 | 0.90 | MEN1 (0.38) | TSHRCYP3A4CA2ALDH1A1MEN1 | |
| SCHEMBL1727003 | 0.85 | TSHR (0.43) | TSHRCYP3A4CA2CA1TDP1 | |
| SCHEMBL8958353 | 0.85 | TSHR (0.43) | TSHRCYP3A4CA2CA1TDP1 | |
| SCHEMBL25220010 | 0.82 | CA2 (0.37) | CA2ALDH1A1 | |
| SCHEMBL5376990 | 0.82 | CA2 (0.37) | CA2ALDH1A1 | |
| SCHEMBL16106544 | 0.82 | CA2 (0.37) | CA2ALDH1A1 | |
| SCHEMBL5377576 | 0.82 | CA2 (0.37) | CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103360421-A | Making method of high purity sulfydryl silicane compound | DAISO CO LTD | 2013-10-23 | — | — | CN | claimed |
| CN-103360421-A | Making method of high purity sulfydryl silicane compound | DAISO CO LTD | 2013-10-23 | — | — | CN | disclosed |
| EP-0190042-B1 | ORGANIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | Lilly Industries Limited (GB) | 1991-10-30 | — | — | EP | disclosed |
| US-4675335-A | LEUKOTRIENE ANTAGONISTS | LILLY INDUSTRIES LIMITED (GB) | 1987-06-23 | — | — | US | disclosed |
| EP-0190042-A2 | Organic compounds and their pharmaceutical use | Lilly Industries Limited (GB) | 1986-08-06 | — | — | EP | disclosed |