Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.50 |
| ▸ | RELA | Q04206 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727008 | 1.00 | PTGER4 (0.52) | PTGER4PTGER3PTGER2PTGER1NFKB1 | |
| SCHEMBL16928592 | 0.88 | MAOB (0.59) | PTGER4PTGER3PTGER2PTGER1MAOB | |
| SCHEMBL16928593 | 0.88 | MAOB (0.59) | PTGER4PTGER3PTGER2PTGER1MAOB | |
| SCHEMBL1728134 | 0.84 | NFKB1 (0.65) | NFKB1NFKB2RELAMAOBMAOA | |
| SCHEMBL1728137 | 0.84 | NFKB1 (0.65) | NFKB1NFKB2RELAMAOBMAOA | |
| SCHEMBL30383381 | 0.84 | NFKB1 (0.61) | NFKB1NFKB2RELAMAOBSLC5A1 | |
| SCHEMBL1728221 | 0.84 | NFKB1 (0.61) | NFKB1NFKB2RELAMAOBSLC5A1 | |
| SCHEMBL1728224 | 0.84 | NFKB1 (0.61) | NFKB1NFKB2RELAMAOBSLC5A1 | |
| SCHEMBL26605004 | 0.83 | AURKA (0.61) | MAOBMAOA | |
| SCHEMBL25283130 | 0.82 | NFKB1 (0.69) | NFKB1NFKB2RELAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609798-B1 | FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | KISSEI PHARMACEUTICAL (JP) | 2012-05-09 | — | — | EP | disclosed |
| EP-1609798-A9 | FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-20060247179-A1 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1609798-A1 | FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247179-A1 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | SLC5A1, SLC5A2, GPR119 | PTGER4 2671/4885PTGER3 1802/4885PTGER2 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.