Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27803762 | 0.83 | SIGMAR1 (0.52) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10756071 | 0.81 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL13995917 | 0.81 | TACR1 (0.46) | TACR1BCHETSHRSIGMAR1CA1 | |
| SCHEMBL7265738 | 0.81 | CA1 (0.47) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL12018717 | 0.81 | CA1 (0.47) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL7265733 | 0.81 | CA1 (0.47) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL21755741 | 0.80 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL6119036 | 0.79 | FOLH1 (0.48) | TACR1CA1CA2CA7CA9 | |
| SCHEMBL8327295 | 0.79 | IDO1 (0.40) | TACR1BCHE | |
| SCHEMBL15341689 | 0.78 | BCHE (0.43) | TACR1BCHETSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |