Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27803762 | 0.92 | SIGMAR1 (0.52) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL10756071 | 0.90 | SIGMAR1 (0.50) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL27919298 | 0.89 | SIGMAR1 (0.46) | SIGMAR1POLB | |
| SCHEMBL9063683 | 0.88 | SIGMAR1 (0.55) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL20794423 | 0.86 | TLR2 (0.49) | SIGMAR1 | |
| SCHEMBL18844905 | 0.86 | TLR2 (0.49) | SIGMAR1 | |
| SCHEMBL1851333 | 0.85 | SIGMAR1 (0.46) | SIGMAR1POLBCYP3A4ALDH1A1THRB | |
| SCHEMBL18741367 | 0.85 | SIGMAR1 (0.50) | SIGMAR1POLBKMT2AMEN1 | |
| SCHEMBL26180478 | 0.85 | SIGMAR1 (0.46) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL12138912 | 0.85 | SIGMAR1 (0.46) | SIGMAR1POLBCYP3A4ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062768-A1 | CX3CR1 Small Molecule Antagonists, and Methods Using Same | DREXEL UNIVERSITY | 2020-02-27 | — | — | US | disclosed |
| CN-103298772-B | Method for producing aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL CO | 2015-06-24 | — | — | CN | disclosed |
| CN-103298772-A | Method for producing aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL CO | 2013-09-11 | — | — | CN | disclosed |
| CN-101951771-A | Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens | SUMITOMO CHEMICAL CO | 2011-01-19 | — | — | CN | disclosed |
| CN-1181690-A | Herbicidal aza bisphosphonic acids and compsns. containing the same | ZENECA LTD (GB) | 1998-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062768-A1 | CX3CR1 Small Molecule Antagonists, and Methods Using Same | CX3CR1, CCR5, CXCR3 | SIGMAR1 355/4885POLB 4422/4885KDM4E 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.