Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206811 | 0.99 | HDAC1 (0.64) | HDAC1HDAC6PPARAPPARGMTNR1A | |
| SCHEMBL1856638 | 0.94 | PPARA (0.59) | HDAC1HDAC6PPARAPPARGMTNR1A | |
| SCHEMBL1802183 | 0.89 | ALDH1A1 (0.56) | HDAC1HDAC6PPARAPPARGMTNR1A | |
| SCHEMBL3145595 | 0.87 | HDAC1 (0.75) | HDAC1HDAC6MTNR1AMTNR1BEPHX2 | |
| SCHEMBL28189232 | 0.87 | HDAC1 (0.60) | HDAC1HDAC6PPARAPPARGMTNR1A | |
| SCHEMBL4249861 | 0.87 | PPARA (0.51) | HDAC1HDAC6PPARAPPARGMTNR1A | |
| SCHEMBL17274778 | 0.87 | PPARA (0.83) | HDAC1HDAC6PPARAPPARG | |
| SCHEMBL5276845 | 0.86 | CNR1 (0.50) | HDAC1HDAC6PPARAPPARG | |
| SCHEMBL12698686 | 0.86 | HDAC1 (0.72) | HDAC1HDAC6MTNR1AMTNR1BEPHX2 | |
| SCHEMBL765019 | 0.85 | PPARA (0.56) | HDAC1HDAC6PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121268-A1 | PPAR MODULATORS | ROMEIRO LUIZ ANTONIO SOARES (BR) | 2017-05-04 | — | — | US | disclosed |
| US-20170121268-A1 | PPAR MODULATORS | ROMEIRO LUIZ ANTONIO SOARES (BR) | 2017-05-04 | — | — | US | disclosed |
| US-20170121268-A1 | PPAR MODULATORS | ROMEIRO LUIZ ANTONIO SOARES (BR) | 2017-05-04 | — | — | US | disclosed |
| WO-2015176153-A1 | PPAR MODULATORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015176153-A1 | PPAR MODULATORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121268-A1 | PPAR MODULATORS | GPR119, FABP2, HDLBP | HDAC1 2184/4885HDAC6 2051/4885PPARA 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.