Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276373 | 0.81 | HPGD (0.49) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL17276563 | 0.80 | HPGD (0.47) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL17276552 | 0.80 | HPGD (0.51) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL17276367 | 0.80 | CNR1 (0.48) | — | |
| SCHEMBL19078698 | 0.79 | FAAH (0.43) | ALDH1A1GRIN2B | |
| SCHEMBL17276317 | 0.79 | NPC1 (0.44) | ALDH1A1GRIN2BTSHRNPC1RAB9A | |
| SCHEMBL17276646 | 0.78 | NPC1 (0.43) | MEN1KMT2APOLBTSHRNPC1 | |
| SCHEMBL17276798 | 0.78 | DAGLA (0.46) | ALDH1A1KMT2APOLBNPC1RAB9A | |
| SCHEMBL19078697 | 0.77 | CCNC (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL17276558 | 0.76 | KDM4E (0.39) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179559-A2 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |