Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 3/20 | 0.39 |
| ▸ | CDK8 | P49336 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276552 | 0.84 | HPGD (0.51) | TSHRALDH1A1LMNA | |
| SCHEMBL17276646 | 0.84 | NPC1 (0.43) | CCNCCDK8TSHRRECQL | |
| SCHEMBL17276373 | 0.83 | HPGD (0.49) | TSHRRECQLALDH1A1LMNA | |
| SCHEMBL17276563 | 0.82 | HPGD (0.47) | ALDH1A1LMNA | |
| SCHEMBL17276798 | 0.81 | DAGLA (0.46) | ALDH1A1 | |
| SCHEMBL17276294 | 0.78 | LMNA (0.47) | ALDH1A1LMNA | |
| SCHEMBL17276317 | 0.78 | NPC1 (0.44) | CCNCCDK8TSHRALDH1A1 | |
| SCHEMBL17276663 | 0.77 | PLA2G7 (0.46) | TSHRALDH1A1LMNA | |
| SCHEMBL17276375 | 0.74 | GAK (0.43) | TSHRALDH1A1 | |
| SCHEMBL19078705 | 0.70 | FAAH (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, FAAH, FAAH2 | CCNC 4720/4885CDK8 2895/4885TSHR 4282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.