Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 15/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 11/20 | 0.52 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17277169 | 1.00 | PRKCQ (0.52) | PRKCQPRKCDPRKCAPIM1MAPT | |
| SCHEMBL9882313 | 0.90 | PRKCQ (0.51) | PRKCQPRKCDPRKCAPIM1MAPT | |
| SCHEMBL9882267 | 0.90 | PRKCQ (0.53) | PRKCQPRKCDPRKCAPIM1MAPT | |
| SCHEMBL9882266 | 0.90 | PRKCQ (0.53) | PRKCQPRKCDPRKCAPIM1MAPT | |
| SCHEMBL15273789 | 0.90 | PRKCQ (0.53) | PRKCQPRKCDPRKCAPIM1MAPT | |
| SCHEMBL15273819 | 0.90 | PRKCQ (0.53) | PRKCQPRKCDPRKCAPIM1MAPT | |
| SCHEMBL17277168 | 0.90 | PRKCQ (0.44) | PRKCQPRKCDPRKCAPIM1 | |
| SCHEMBL17277167 | 0.90 | PRKCQ (0.44) | PRKCQPRKCDPRKCAPIM1 | |
| SCHEMBL9882083 | 0.89 | PRKCQ (0.47) | PRKCQPRKCDPRKCAPIM1MAPT | |
| SCHEMBL9882031 | 0.89 | PRKCQ (0.47) | PRKCQPRKCDPRKCAPIM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193722-B2 | Tri-cyclic pyrazolopyridine kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-11-24 | — | — | US | disclosed |
| US-9193722-B2 | Tri-cyclic pyrazolopyridine kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-11-24 | — | — | US | disclosed |