Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727878 | 0.92 | PDE4A (0.39) | CNR1MAPTSMN1; SMN2PIM1PIM2 | |
| SCHEMBL1730374 | 0.91 | CNR1 (0.44) | CNR1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1727719 | 0.89 | CNR1 (0.46) | CNR1KMT2APIM1PIM2CNR2 | |
| SCHEMBL1730290 | 0.89 | CNR1 (0.43) | CNR1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1728846 | 0.87 | CNR1 (0.43) | CNR1PIM1PIM2 | |
| SCHEMBL1730220 | 0.86 | EGLN1 (0.45) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL1727694 | 0.85 | CNR1 (0.41) | CNR1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL1729333 | 0.85 | SUCNR1 (0.40) | CNR1 | |
| SCHEMBL1727868 | 0.83 | CNR1 (0.43) | CNR1PIM1PIM2 | |
| SCHEMBL1729810 | 0.80 | CNR1 (0.42) | CNR1MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |