Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727868 | 0.92 | CNR1 (0.43) | CNR1PIM1PIM2CTSASIRT5 | |
| SCHEMBL1727719 | 0.87 | CNR1 (0.46) | CNR1PIM1PIM2FAAH | |
| SCHEMBL1729847 | 0.87 | CNR1 (0.43) | CNR1PIM1PIM2CTSAUSP30 | |
| SCHEMBL1727733 | 0.87 | CNR1 (0.45) | CNR1PIM1PIM2 | |
| SCHEMBL1728917 | 0.86 | SLC6A7 (0.40) | CTSAUSP30PDE4DPDE4APDE4B | |
| SCHEMBL1727878 | 0.84 | PDE4A (0.39) | CNR1PIM1PIM2USP30PDE4D | |
| SCHEMBL1727694 | 0.84 | CNR1 (0.41) | CNR1PIM1PIM2FAAH | |
| SCHEMBL1730374 | 0.83 | CNR1 (0.44) | CNR1PIM1PIM2CTSA | |
| SCHEMBL1729333 | 0.80 | SUCNR1 (0.40) | CNR1 | |
| SCHEMBL1728857 | 0.79 | CNR1 (0.42) | CNR1CTSASLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |