Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729810 | 0.91 | CNR1 (0.42) | CNR1MAPTLMNAALDH1A1HPGD | |
| SCHEMBL1727999 | 0.90 | PDE4A (0.40) | CNR1PIM1PIM2PDE4APDE4B | |
| SCHEMBL1727733 | 0.89 | CNR1 (0.45) | CNR1MAPTLMNAALDH1A1HPGD | |
| SCHEMBL1727644 | 0.87 | CNR1 (0.46) | CNR1PIM1PIM2SMN1; SMN2KMT2A | |
| SCHEMBL1729847 | 0.84 | CNR1 (0.43) | CNR1PIM1PIM2PDE4APDE4B | |
| SCHEMBL1728983 | 0.83 | CNR1 (0.40) | CNR1MAPTLMNAALDH1A1HSD17B10 | |
| SCHEMBL1728081 | 0.83 | SUCNR1 (0.40) | — | |
| SCHEMBL1727878 | 0.81 | PDE4A (0.39) | CNR1MAPTHPGDPIM1PIM2 | |
| SCHEMBL1728857 | 0.81 | CNR1 (0.42) | CNR1 | |
| SCHEMBL1730374 | 0.80 | CNR1 (0.44) | CNR1MAPTLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |