Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17277522 | 0.86 | NOS3 (0.30) | — | |
| SCHEMBL17277594 | 0.85 | F2 (0.37) | F2KMT2ATACR1SMN1; SMN2 | |
| SCHEMBL17277450 | 0.84 | F2 (0.37) | F2KMT2ATACR1SMN1; SMN2 | |
| SCHEMBL17277605 | 0.82 | TAAR1 (0.38) | F2KMT2ATACR1SMN1; SMN2 | |
| SCHEMBL12062333 | 0.82 | — | — | |
| SCHEMBL17484567 | 0.81 | F2 (0.35) | F2KMT2ATACR1SMN1; SMN2 | |
| SCHEMBL17277614 | 0.76 | ADRB2 (0.35) | F2KMT2ASMN1; SMN2 | |
| SCHEMBL17277596 | 0.75 | F2 (0.41) | F2KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20082593 | 0.75 | TACR1 (0.33) | F2KMT2ATACR1 | |
| SCHEMBL17277446 | 0.74 | F2 (0.36) | F2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488525-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-9193731-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-11-24 | — | — | US | disclosed |