Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 12/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265721 | 0.85 | CHRM4 (0.45) | CHRM4CHRM2ABL1CHRM1 | |
| SCHEMBL3270574 | 0.84 | CHRM4 (0.44) | CHRM4CHRM2ABL1CHRM1CHRM3 | |
| SCHEMBL1730076 | 0.81 | CHRM4 (0.46) | CHRM4CHRM2MAOAMAOBCHRM1 | |
| SCHEMBL1727574 | 0.78 | CHRM4 (0.38) | CHRM4ABL1 | |
| SCHEMBL1728139 | 0.78 | CHRM4 (0.39) | CHRM4ABL1 | |
| SCHEMBL1729026 | 0.77 | CHRM4 (0.59) | CHRM4CHRM2 | |
| SCHEMBL1728734 | 0.76 | CHRM4 (0.51) | CHRM4CHRM2CHRM1 | |
| SCHEMBL5240063 | 0.74 | AKR1C3 (0.46) | ABL1CHRM1 | |
| SCHEMBL20445945 | 0.74 | CHRM2 (0.45) | CHRM4CHRM2 | |
| SCHEMBL1728885 | 0.74 | CHRM4 (0.53) | CHRM4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |