Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 13/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728734 | 0.87 | CHRM4 (0.51) | CHRM4CHRM2CHRM1 | |
| SCHEMBL1728885 | 0.85 | CHRM4 (0.53) | CHRM4 | |
| SCHEMBL1728730 | 0.84 | MAOA (0.55) | CHRM4MAOAMAOBCHRM2CHRM1 | |
| SCHEMBL346050 | 0.84 | HRH3 (0.56) | CHRM4MAOAMAOBSCD | |
| SCHEMBL3266255 | 0.83 | FAAH (0.44) | CHRM4MAOAMAOBSCDCHRM2 | |
| SCHEMBL1728774 | 0.83 | HRH3 (0.55) | CHRM4MAOAMAOBSCDCHRM2 | |
| SCHEMBL1727780 | 0.81 | CHRM4 (0.52) | CHRM4MAOAMAOBCHRM2CHRM1 | |
| SCHEMBL1728738 | 0.81 | CHRM4 (0.50) | CHRM4MAOAMAOBCHRM2CHRM1 | |
| SCHEMBL1727743 | 0.79 | SIRT2 (0.50) | CHRM4MAOAMAOBCHRM1 | |
| SCHEMBL1730265 | 0.79 | SIRT2 (0.50) | CHRM4MAOAMAOBCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |