Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270238 | 0.84 | CHRM4 (0.51) | CHRM4DRD3DRD2HTR2AHTR2C | |
| SCHEMBL1728004 | 0.83 | HCAR2 (0.53) | CHRM4HTR3A | |
| SCHEMBL3265668 | 0.82 | CHRM4 (0.51) | CHRM4DRD3DRD2HTR2AHTR2C | |
| SCHEMBL1728734 | 0.81 | CHRM4 (0.51) | CHRM4HTR3ACHRM2 | |
| SCHEMBL5800979 | 0.79 | HTR3A (0.58) | DRD3DRD2HTR2AHTR2CHTR3A | |
| SCHEMBL1727542 | 0.79 | HRH3 (0.52) | DRD3DRD2 | |
| SCHEMBL1727780 | 0.77 | CHRM4 (0.52) | CHRM4CHRM2 | |
| SCHEMBL1729269 | 0.77 | AKR1C3 (0.45) | CHRM4DRD3DRD2HTR2AHTR2C | |
| SCHEMBL1730124 | 0.77 | CHRM4 (0.46) | CHRM4DRD3DRD2HTR2AHTR2C | |
| SCHEMBL1728813 | 0.76 | SIRT2 (0.51) | CHRM4DRD2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |