Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.45 |
| ▸ | GBA1 | P04062 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17278246 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2TNFALDH1A1 | |
| SCHEMBL15581551 | 1.00 | GJB2 (0.45) | GJB2GBA1SMN1; SMN2TNFALDH1A1 | |
| SCHEMBL14012378 | 0.95 | GJB2 (0.48) | GJB2GBA1SMN1; SMN2TNFALDH1A1 | |
| SCHEMBL12000785 | 0.87 | SMN1; SMN2 (0.42) | GJB2GBA1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL14418558 | 0.86 | GBA1 (0.46) | GJB2GBA1SMN1; SMN2TNFALDH1A1 | |
| SCHEMBL14392184 | 0.86 | SMN1; SMN2 (0.41) | GJB2GBA1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL469761 | 0.86 | SMN1; SMN2 (0.41) | GJB2GBA1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL10134736 | 0.86 | SMN1; SMN2 (0.41) | GJB2GBA1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL15255412 | 0.86 | SMN1; SMN2 (0.41) | GJB2GBA1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL12556188 | 0.86 | SMN1; SMN2 (0.41) | GJB2GBA1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015177083-A1 | STEREOSELECTIVE SYNTHESIS OF INTERMEDIATES IN THE PREPARATION OF ß-C-ARYLGLUCOSIDES | LEK PHARMACEUTICALS D.D. (SI) | 2015-11-26 | — | — | WO | disclosed |
| EP-2947077-A1 | Stereoselective synthesis of intermediates in the preparation of ß-C-arylglucosides | LEK Pharmaceuticals d.d. (SI) | 2015-11-25 | — | — | EP | disclosed |