Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268922 | 0.83 | NOTUM (0.46) | NOTUMPOLBLMNAHTTALDH1A1 | |
| SCHEMBL3265530 | 0.81 | POLB (0.46) | NOTUMPOLBLMNAKMT2AALDH1A1 | |
| SCHEMBL3266868 | 0.81 | NOTUM (0.47) | NOTUMPOLBLMNAHTTCHRM4 | |
| SCHEMBL1727477 | 0.79 | CHRM4 (0.66) | NOTUMPOLBLMNAHTTCHRM4 | |
| SCHEMBL1729831 | 0.79 | NOTUM (0.47) | NOTUMPOLBLMNAHTTCHRM4 | |
| Lithium Ion SCHEMBL31016628 | 0.78 | NOTUM (0.53) | NOTUMPOLBLMNAHTTKMT2A | |
| SCHEMBL25080907 | 0.76 | NOTUM (0.54) | NOTUMPOLBCHRM4DRD2ALDH1A1 | |
| SCHEMBL1410310 | 0.75 | NOTUM (0.66) | NOTUMPOLBLMNAHTTCHRM4 | |
| SCHEMBL1729137 | 0.74 | NOTUM (0.49) | NOTUMPOLBLMNAHTTKMT2A | |
| SCHEMBL1728028 | 0.74 | NOTUM (0.47) | NOTUMPOLBLMNAHTTCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |