Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728028 | 0.86 | NOTUM (0.47) | NOTUMPOLBLMNAKMT2AHTT | |
| SCHEMBL1729829 | 0.84 | NOTUM (0.47) | NOTUMPOLBLMNAKMT2AHTT | |
| SCHEMBL1729831 | 0.83 | NOTUM (0.47) | NOTUMPOLBLMNAHTTALDH1A1 | |
| SCHEMBL1729365 | 0.82 | NOTUM (0.52) | NOTUMPOLBLMNAKMT2AHTT | |
| SCHEMBL1727883 | 0.74 | NOTUM (0.55) | NOTUMPOLBLMNAKMT2AHTT | |
| Lithium Ion SCHEMBL31016628 | 0.72 | NOTUM (0.53) | NOTUMPOLBLMNAKMT2AHTT | |
| SCHEMBL3268922 | 0.72 | NOTUM (0.46) | NOTUMPOLBLMNAHTTALDH1A1 | |
| SCHEMBL1410310 | 0.70 | NOTUM (0.66) | NOTUMPOLBLMNAKMT2AHTT | |
| SCHEMBL1727951 | 0.69 | NOTUM (0.49) | NOTUMPOLBLMNAKMT2AHTT | |
| SCHEMBL1729795 | 0.69 | LMNA (0.60) | LMNAKMT2AHTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |