Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355253 | 0.83 | GAA (0.55) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL14519887 | 0.80 | GAA (0.42) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL18018774 | 0.79 | GAA (0.46) | SMN1; SMN2GAAMGAMSIMGAM2 | |
| SCHEMBL27407145 | 0.78 | LMNA (0.40) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL28604705 | 0.77 | LMNA (0.48) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL154280 | 0.77 | GAA (0.53) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL11651480 | 0.77 | LMNA (0.48) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL12989511 | 0.77 | GAA (0.39) | LMNASMN1; SMN2GAAALDH1A1HSD17B10 | |
| SCHEMBL9258313 | 0.76 | GAA (0.44) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL605889 | 0.75 | GAA (0.48) | SMN1; SMN2GAAALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9332762-B2 | Method for preparing amicarbazone | KS LABORATORIES CO., LTD. (KR) | 2016-05-10 | — | — | US | disclosed |
| US-20150336906-A1 | METHOD FOR PREPARING AMICARBAZONE | KS LABORATORIES CO., LTD. (KR) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336906-A1 | METHOD FOR PREPARING AMICARBAZONE | CYP2J2, CPS1, AURKA | LMNA 2715/4885SMN1; SMN2 4679/4885GAA 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.