SCHEMBL17280422

SCHEMBL17280422

CCC1NC(=O)N(c2ccc(Oc3ccc(C)c4c3C(C)(C)CO4)nc2)C1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30939606 1.00 MMP13 (0.30) MMP13
SCHEMBL9904821 1.00 MMP13 (0.30) MMP13
SCHEMBL19846867 0.90
SCHEMBL30939535 0.90
SCHEMBL30939534 0.90
SCHEMBL9904667 0.90
SCHEMBL17280423 0.89
SCHEMBL15011856 0.89
SCHEMBL30939643 0.89
SCHEMBL21857962 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10555945-B2 Compounds AUTIFONY THERAPEUTICS LIMITED (GB) 2020-02-11 US disclosed
US-20190000849-A1 NOVEL COMPOUNDS AUTIFONY THERAPEUTICS LIMITED 2019-01-03 US disclosed
US-20180036308-A1 NOVEL COMPOUNDS AUTIFONY SRL (IT) 2018-02-08 US disclosed
US-20180036308-A1 NOVEL COMPOUNDS AUTIFONY SRL (IT) 2018-02-08 US disclosed
US-20160317537-A1 NOVEL COMPOUNDS AUTIFONY SRL (IT) 2016-11-03 US disclosed
US-20160317537-A1 NOVEL COMPOUNDS AUTIFONY SRL (IT) 2016-11-03 US disclosed
US-9422272-B2 Compounds AUTIFONY THERAPEUTICS LIMITED (GB) 2016-08-23 US disclosed
US-9422272-B2 Compounds AUTIFONY THERAPEUTICS LIMITED (GB) 2016-08-23 US disclosed
US-20150336936-A1 NOVEL COMPOUNDS AUTIFONY SRL (IT) 2015-11-26 US disclosed
US-20150336936-A1 NOVEL COMPOUNDS AUTIFONY SRL (IT) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336936-A1 NOVEL COMPOUNDS KCNN3, KCNN2, KCNN1 MMP13 4640/4885
US-20190000849-A1 NOVEL COMPOUNDS KCNN3, KCND3, KCNA3 MMP13 4544/4885
US-20160317537-A1 NOVEL COMPOUNDS KCNN3, KCNN2, KCNN1 MMP13 4640/4885
US-10555945-B2 Compounds KCNN3, KCNA3, KCNQ3 MMP13 4302/4885
US-20180036308-A1 NOVEL COMPOUNDS CYFIP1, CYFIP2, ZFX MMP13 4712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.