⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280432 | 0.94 | — | — | |
| SCHEMBL17280440 | 0.89 | — | — | |
| SCHEMBL17278382 | 0.88 | CA1 (0.31) | — | |
| SCHEMBL17277975 | 0.88 | CA1 (0.31) | — | |
| SCHEMBL17278383 | 0.88 | — | — | |
| SCHEMBL17280449 | 0.86 | CA1 (0.31) | — | |
| SCHEMBL19754863 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL17277977 | 0.81 | CA1 (0.33) | — | |
| SCHEMBL13925570 | 0.81 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL17280430 | 0.80 | HSD17B10 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840524-B2 | Process for reducing the chlorine content of organomonophosphites using two solutions | EVONIK DEGUSSA GMBH (DE) | 2017-12-12 | — | — | US | disclosed |
| US-9751904-B2 | Method for reducing the chlorine content of organomonophosphites using dimethylaminobutane, triethylamine or triethanolamine | EVONIK DEGUSSA GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20170121355-A1 | PROCESS FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING TWO SOLUTIONS | EVONIK DEGUSSA GMBH (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20170088570-A1 | METHOD FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING DIMETHYLAMINOBUTANE, TRIETHYLAMINE OR TRIETHANOLAMINE | EVONIK DEGUSSA GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| US-9605010-B2 | Monophosphite compounds having a methyl group | EVONIK DEGUSSA GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| US-9605011-B2 | Monophosphite compounds having an ether group | EVONIK DEGUSSA GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| US-20160318960-A1 | NOVEL MONOPHOSPHITE COMPOUNDS HAVING AN ETHER GROUP | EVONIK DEGUSSA GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160318959-A1 | NOVEL MONOPHOSPHITE COMPOUNDS HAVING A METHYL GROUP | EVONIK DEGUSSA GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9221850-B2 | Monophosphite ligands having a tert-butyloxycarbonyl group | EVONIK INDUSTRIES AG (DE) | 2015-12-29 | — | — | US | disclosed |
| US-9212195-B1 | Monophosphite ligands having a carbonate group | EVONIK INDUSTRIES AG (DE) | 2015-12-15 | — | — | US | disclosed |
| US-20150336988-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A TERT-BUTYLOXYCARBONYL GROUP | EVONIK INDUSTRIES AG (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150336987-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A CARBONATE GROUP | EVONIK INDUSTRIES AG (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150099737-A1 | PYRROLOPYRIMIDINE COMPOUNDS AS INHIBITORS OF CDK4/6 | NOVARTIS AG (CH) | 2015-04-09 | — | — | US | disclosed |