Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280445 | 0.90 | RXRA (0.32) | HSD17B10 | |
| SCHEMBL17280433 | 0.88 | NPC1 (0.31) | — | |
| SCHEMBL12266789 | 0.88 | ALDH1A1 (0.31) | — | |
| SCHEMBL17277948 | 0.88 | CA1 (0.32) | HSD17B10 | |
| SCHEMBL17277963 | 0.87 | MAPT (0.32) | HSD17B10 | |
| SCHEMBL17278383 | 0.82 | — | — | |
| SCHEMBL9685233 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL15356799 | 0.81 | CA1 (0.33) | — | |
| SCHEMBL17280431 | 0.80 | — | — | |
| SCHEMBL12266786 | 0.80 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840524-B2 | Process for reducing the chlorine content of organomonophosphites using two solutions | EVONIK DEGUSSA GMBH (DE) | 2017-12-12 | — | — | US | disclosed |
| US-9751904-B2 | Method for reducing the chlorine content of organomonophosphites using dimethylaminobutane, triethylamine or triethanolamine | EVONIK DEGUSSA GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20170121355-A1 | PROCESS FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING TWO SOLUTIONS | EVONIK DEGUSSA GMBH (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20170088570-A1 | METHOD FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING DIMETHYLAMINOBUTANE, TRIETHYLAMINE OR TRIETHANOLAMINE | EVONIK DEGUSSA GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| US-9605010-B2 | Monophosphite compounds having a methyl group | EVONIK DEGUSSA GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| US-9605011-B2 | Monophosphite compounds having an ether group | EVONIK DEGUSSA GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| US-20160318960-A1 | NOVEL MONOPHOSPHITE COMPOUNDS HAVING AN ETHER GROUP | EVONIK DEGUSSA GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160318959-A1 | NOVEL MONOPHOSPHITE COMPOUNDS HAVING A METHYL GROUP | EVONIK DEGUSSA GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9221850-B2 | Monophosphite ligands having a tert-butyloxycarbonyl group | EVONIK INDUSTRIES AG (DE) | 2015-12-29 | — | — | US | disclosed |
| US-9212195-B1 | Monophosphite ligands having a carbonate group | EVONIK INDUSTRIES AG (DE) | 2015-12-15 | — | — | US | disclosed |
| US-20150336988-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A TERT-BUTYLOXYCARBONYL GROUP | EVONIK INDUSTRIES AG (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150336987-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A CARBONATE GROUP | EVONIK INDUSTRIES AG (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318960-A1 | NOVEL MONOPHOSPHITE COMPOUNDS HAVING AN ETHER GROUP | NUDT1, PHOSPHO1, NUDT14 | HSD17B10 4079/4885 |
| US-20170121355-A1 | PROCESS FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING TWO SOLUTIONS | PHOSPHO1, PLCG2, PLCG1 | HSD17B10 3842/4885 |
| US-20150336988-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A TERT-BUTYLOXYCARBONYL GROUP | TERF2, NUDT1, TERF2IP | HSD17B10 3043/4885 |
| US-20170088570-A1 | METHOD FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING DIMETHYLAMINOBUTANE, TRIETHYLAMINE OR TRIETHANOLAMINE | PHOSPHO1, SGMS2, SGMS1 | HSD17B10 3805/4885 |
| US-20150336987-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A CARBONATE GROUP | M6PR, NUDT1, PHOSPHO1 | HSD17B10 3960/4885 |
| US-20160318959-A1 | NOVEL MONOPHOSPHITE COMPOUNDS HAVING A METHYL GROUP | NUDT1, MTAP, MPHOSPH6 | HSD17B10 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.