SCHEMBL17280477

SCHEMBL17280477

Cc1cc(N=Nc2ccc3cc(Nc4ccccc4)ccc3c2O)c(C)cc1N=Nc1ccc(N=Nc2c(C)cc(N=Nc3cc4c(S(=O)(=O)O)cccc4cc3S(=O)(=O)O)cc2C)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 9/20 0.50
PHLPP2 Q6ZVD8 2/20 0.44
ALDH1A1 P00352 1/20 0.43
HIF1A Q16665 1/20 0.43
CD40 P25942 1/20 0.42
CD40LG P29965 1/20 0.42
MPL P40238 1/20 0.42
CTRC Q99895 1/20 0.42
PRMT3 O60678 1/20 0.41
EP300 Q09472 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
PRMT1 Q99873 1/20 0.41
CTRB1 P17538 1/20 0.41
ATIC P31939 1/20 0.40
SUMO2 P61956 1/20 0.40
SUMO1 P63165 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP2 Q9HC62 1/20 0.40
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935118 1.00 ENPP2 (0.50) ENPP2PHLPP2ALDH1A1HIF1ACD40
SCHEMBL15935133 0.96 ENPP2 (0.49) ENPP2PHLPP2ALDH1A1HIF1ACD40
SCHEMBL15935144 0.95 ENPP2 (0.49) ENPP2PHLPP2ALDH1A1HIF1ACD40
SCHEMBL19958064 0.93 ENPP2 (0.49) ENPP2PHLPP2ALDH1A1HIF1ACD40
SCHEMBL15935109 0.92 ENPP2 (0.53) ENPP2PHLPP2ALDH1A1HIF1AMPL
SCHEMBL19958118 0.92 ENPP2 (0.53) ENPP2PHLPP2ALDH1A1HIF1AMPL
SCHEMBL17280478 0.91 ENPP2 (0.50) ENPP2ALDH1A1HIF1ACD40CD40LG
SCHEMBL15385554 0.91 ENPP2 (0.51) ENPP2PHLPP2ALDH1A1HIF1ACD40
SCHEMBL15385555 0.91 ENPP2 (0.51) ENPP2PHLPP2ALDH1A1HIF1ACD40
SCHEMBL17460855 0.90 ENPP2 (0.59) ENPP2PHLPP2ALDH1A1HIF1ACD40

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 ENPP2 2889/4885PHLPP2 770/4885ALDH1A1 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.