Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | DAGLB | Q8NCG7 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727999 | 0.92 | PDE4A (0.40) | TGM2ABL1SCN9A | |
| SCHEMBL1729810 | 0.90 | CNR1 (0.42) | TGM2HTR1ADRD2DRD4HTR2A | |
| SCHEMBL1729333 | 0.87 | SUCNR1 (0.40) | SUCNR1DAGLATGM2EPHB4TEK | |
| SCHEMBL1728983 | 0.87 | CNR1 (0.40) | TGM2HTR1ADRD2DRD4HTR2A | |
| SCHEMBL1728857 | 0.84 | CNR1 (0.42) | TGM2SCN9AHTR1ADRD2DRD4 | |
| SCHEMBL1729020 | 0.84 | SCN10A (0.38) | TEKSCN10AHTR1ADRD4HTR2A | |
| SCHEMBL1730290 | 0.83 | CNR1 (0.43) | — | |
| SCHEMBL1727644 | 0.81 | CNR1 (0.46) | TGM2 | |
| SCHEMBL1728823 | 0.81 | SLC6A7 (0.44) | SCN9A | |
| SCHEMBL1727878 | 0.79 | PDE4A (0.39) | TGM2ABL1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |