SCHEMBL17281116

SCHEMBL17281116

CCCCC(=O)c1ccc(N(c2ccccc2)c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP5 P45974 1/20 0.55
HSD17B3 P37058 7/20 0.50
HTR7 P34969 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HPGD P15428 1/20 0.45
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
POLB P06746 1/20 0.42
STS P08842 1/20 0.42
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17281117 0.94 USP5 (0.57) USP5HSD17B3HTR7L3MBTL1NPC1
SCHEMBL20099132 0.89 HSD17B3 (0.48) USP5HSD17B3HTR7L3MBTL1SMN1; SMN2
SCHEMBL5566974 0.87 USP5 (0.66) USP5HSD17B3HTR7L3MBTL1SMN1; SMN2
SCHEMBL9718456 0.85 HSD17B3 (0.62) HSD17B3HTR7L3MBTL1SMN1; SMN2HPGD
SCHEMBL17284938 0.84 HSD17B3 (0.54) HSD17B3HTR7L3MBTL1SMN1; SMN2HPGD
SCHEMBL11267981 0.84 HSD17B3 (0.63) HSD17B3HTR7L3MBTL1SMN1; SMN2HPGD
SCHEMBL21524740 0.83 HSD17B3 (0.53) USP5HSD17B3HTR7L3MBTL1NPC1
SCHEMBL21524749 0.83 HSD17B3 (0.53) HSD17B3HTR7L3MBTL1SMN1; SMN2HPGD
SCHEMBL30871980 0.82 HSD17B3 (0.66) USP5HSD17B3HTR7L3MBTL1STS
SCHEMBL4871741 0.78 USP5 (0.72) USP5HSD17B3HTR7L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840397-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2020-11-17 US disclosed
US-10461201-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2019-10-29 US disclosed
US-20190284471-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES CHOSHU INDUSTRY CO., LTD. (JP) 2019-09-19 US disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 US disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed