SCHEMBL17281117

SCHEMBL17281117

CCCCC(=O)c1ccc(N(c2ccc(C(=O)CCCC)cc2)c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP5 P45974 1/20 0.57
HSD17B3 P37058 8/20 0.56
HTR7 P34969 1/20 0.54
STS P08842 1/20 0.46
THRA P10827 2/20 0.45
THRB P10828 2/20 0.45
CNR2 P34972 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
POLB P06746 1/20 0.42
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17281116 0.94 USP5 (0.55) USP5HSD17B3HTR7STSTHRA
SCHEMBL5566974 0.92 USP5 (0.66) USP5HSD17B3HTR7STSTHRA
SCHEMBL21524740 0.88 HSD17B3 (0.53) USP5HSD17B3HTR7STSTHRA
SCHEMBL30871980 0.87 HSD17B3 (0.66) USP5HSD17B3HTR7STSTHRA
SCHEMBL20099132 0.83 HSD17B3 (0.48) USP5HSD17B3HTR7STSTHRA
SCHEMBL4871741 0.83 USP5 (0.72) USP5HSD17B3HTR7L3MBTL1MEN1
SCHEMBL17284936 0.82 HSD17B3 (0.61) HSD17B3HTR7STSTHRATHRB
SCHEMBL11464173 0.81 USP5 (0.70) USP5HSD17B3HTR7STSL3MBTL1
SCHEMBL19992576 0.81 HSD17B3 (0.59) HSD17B3HTR7STSTHRATHRB
SCHEMBL20099134 0.79 L3MBTL1 (0.61) HSD17B3HTR7THRATHRBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840397-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2020-11-17 US disclosed
US-10461201-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2019-10-29 US disclosed
US-20190284471-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES CHOSHU INDUSTRY CO., LTD. (JP) 2019-09-19 US disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 US disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed