Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAC2 | P15153 | 1/20 | 0.33 |
| ▸ | RAC3 | P60763 | 1/20 | 0.33 |
| ▸ | CDC42 | P60953 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951244 | 0.89 | KDM4E (0.53) | KDM4EL3MBTL1ATMPTGER4ALDH1A1 | |
| SCHEMBL17228176 | 0.85 | KDM4E (0.56) | KDM4EL3MBTL1ATMPTGER4ALDH1A1 | |
| SCHEMBL15773382 | 0.85 | KDM4E (0.41) | KDM4EL3MBTL1ATMPTGER4ALDH1A1 | |
| SCHEMBL17282459 | 0.85 | KDM4E (0.41) | KDM4EL3MBTL1ATMPTGER4ALDH1A1 | |
| SCHEMBL15773363 | 0.85 | PTGER4 (0.49) | KDM4EL3MBTL1ATMPTGER4ALDH1A1 | |
| SCHEMBL15773354 | 0.85 | ESR1 (0.49) | KDM4EL3MBTL1ATMPTGER4ALDH1A1 | |
| SCHEMBL9890222 | 0.85 | KDM4E (0.46) | KDM4EL3MBTL1ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL19797683 | 0.85 | L3MBTL1 (0.69) | KDM4EL3MBTL1ATMALDH1A1MAPK1 | |
| SCHEMBL26809712 | 0.85 | L3MBTL1 (0.69) | KDM4EL3MBTL1ATMALDH1A1MAPK1 | |
| SCHEMBL17228195 | 0.85 | L3MBTL1 (0.69) | KDM4EL3MBTL1ATMALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2926385-B1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-08-05 | — | — | EP | disclosed |
| US-20150336959-A1 | Electronic Device | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150336959-A1 | Electronic Device | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336959-A1 | Electronic Device | ETFB, ETFA, XPOT | KDM4E 3240/4885L3MBTL1 4434/4885ATM 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.