⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3804136 | 0.78 | — | — | |
| SCHEMBL11089123 | 0.74 | — | — | |
| SCHEMBL762994 | 0.74 | — | — | |
| SCHEMBL21316634 | 0.74 | — | — | |
| SCHEMBL7814837 | 0.73 | — | — | |
| SCHEMBL13750213 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL4316750 | 0.72 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL7817837 | 0.70 | — | — | |
| SCHEMBL11289113 | 0.70 | — | — | |
| SCHEMBL5962515 | 0.69 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461346-B2 | Benzyl amines, a process for their production and their use as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-06-11 | — | — | US | claimed |
| US-20120289510-A1 | Benzyl Amines, A Process For Their Production And Their Use As Anti-Inflammtory Agents | ASTRAZENECA AB (SE) | 2012-11-15 | — | — | US | claimed |
| WO-2012025578-A3 | AN APPLICATOR FOR APPLYING A COSMETIC COMPOSITION AND A COSMETIC PACKAGING INCLUDING SUCH AN APPLICATOR | ALBEA SERVICES (FR) | 2012-05-10 | — | — | WO | claimed |
| US-8173676-B2 | Benzyl, amines, a process for their production and their use as anti-inflammatory agents | Bayer Pharma AG (DE) | 2012-05-08 | — | — | US | claimed |
| EP-2041069-B1 | BENZYL AMINES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Bayer Pharma AG (DE) | 2011-11-30 | — | — | EP | claimed |
| US-7999108-B2 | Benzyl amines, a process for their production and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AG (DE) | 2011-08-16 | — | — | US | claimed |
| US-20080032986-A1 | BENZYL AMINES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-02-07 | — | — | US | claimed |
| EP-1878717-A1 | Benzyl amines, a process for their production and their use as anti-inflammatory agents | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-01-16 | — | — | EP | claimed |
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | claimed |
| EP-0671401-A1 | Beta lactames | F. HOFFMANN-LA ROCHE AG (CH) | 1995-09-13 | — | — | EP | claimed |
| EP-0055562-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1986-02-12 | — | — | EP | claimed |
| US-4492692-A | BACTERICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | claimed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | claimed |
| US-8461346-B2 | Benzyl amines, a process for their production and their use as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-06-11 | — | — | US | disclosed |
| US-20120289510-A1 | Benzyl Amines, A Process For Their Production And Their Use As Anti-Inflammtory Agents | ASTRAZENECA AB (SE) | 2012-11-15 | — | — | US | disclosed |
| WO-2012025578-A3 | AN APPLICATOR FOR APPLYING A COSMETIC COMPOSITION AND A COSMETIC PACKAGING INCLUDING SUCH AN APPLICATOR | ALBEA SERVICES (FR) | 2012-05-10 | — | — | WO | disclosed |
| US-5439904-A | Enzyme inhibitors of human leukocyte elastase; respiratory system disorders; antiarthritic agents | SYNPHAR LABORATORIES, INC. (CA) | 1995-08-08 | — | — | US | disclosed |
| WO-1995015966-A1 | 2-SPIRO(2'-SPIROCYCLOALKYL)CYCLOPROPYL CEPHALOSPORIN SULFONES AS ANTIINFLAMMATORY AND ANTIDEGENERATIVE AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1995-06-15 | — | — | WO | disclosed |
| US-4492692-A | BACTERICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | disclosed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | disclosed |