Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728290 | 1.00 | SMARCA4 (0.33) | SMARCA4KDM4EMEN1KMT2APBRM1 | |
| SCHEMBL1616233 | 0.83 | DDB1 (0.44) | SMARCA4KDM4EMEN1KMT2APBRM1 | |
| SCHEMBL1616234 | 0.83 | DDB1 (0.44) | SMARCA4KDM4EMEN1KMT2APBRM1 | |
| SCHEMBL3664235 | 0.79 | ALDH1A1 (0.44) | SMARCA4KDM4EMEN1KMT2A | |
| SCHEMBL1617137 | 0.78 | MAP1LC3B (0.44) | SMARCA4KDM4EMEN1KMT2A | |
| SCHEMBL1616878 | 0.72 | MAP1LC3B (0.47) | — | |
| SCHEMBL1616876 | 0.72 | MAP1LC3B (0.47) | — | |
| SCHEMBL1617177 | 0.72 | MAP1LC3B (0.47) | KDM4EPBRM1 | |
| SCHEMBL1617176 | 0.72 | MAP1LC3B (0.47) | KDM4EPBRM1 | |
| SCHEMBL1616291 | 0.71 | MAP1LC3B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012030952-A3 | REDUCING RIPPLE CURRENT IN A SWITCHED-MODE POWER CONVERTER EMPLOYING A BRIDGE TOPOLOGY | TEXAS INSTRUMENTS INCORPORATED (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2231629-B1 | MODULATORS FOR AMYLOID BETA | HOFFMANN LA ROCHE (CH) | 2011-11-30 | — | — | EP | disclosed |