SCHEMBL17283236

SCHEMBL17283236

c1ccc(N2c3ccccc3N(c3ccc(-c4nc5cc6oc(-c7ccc(N8c9ccccc9N(c9ccccc9)c9ccccc98)cc7)nc6cc5o4)cc3)c3ccccc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.51
RAB9A P51151 9/20 0.51
SMN1; SMN2 Q16637 8/20 0.48
KDM4E B2RXH2 5/20 0.48
HPGD P15428 5/20 0.48
CASP3 P42574 2/20 0.48
SENP7 Q9BQF6 2/20 0.48
SENP6 Q9GZR1 2/20 0.48
POLB P06746 1/20 0.48
SENP8 Q96LD8 1/20 0.48
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 4/20 0.43
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
MAPT P10636 3/20 0.43
TP53 P04637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ATM Q13315 1/20 0.43
GFER P55789 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283341 0.98 NPC1 (0.50) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17404421 0.95 NPC1 (0.50) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283262 0.92 NPC1 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17404425 0.90 NPC1 (0.48) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283333 0.89 SMN1; SMN2 (0.50) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17038496 0.88 NPC1 (0.66) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283229 0.88 SMN1; SMN2 (0.42) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283338 0.88 SMN1; SMN2 (0.49) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283238 0.87 NPC1 (0.48) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17283339 0.87 NPC1 (0.46) NPC1RAB9ASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2020-08-13 US disclosed
US-9793492-B2 Compound, light emitter, and organic light emitting device KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-10-17 US disclosed
US-9793492-B2 Compound, light emitter, and organic light emitting device KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-10-17 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 US disclosed
WO-2015176981-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2015-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE DDT, DRD1, DRD2 NPC1 3198/4885RAB9A 1696/4885SMN1; SMN2 4840/4885
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.