Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728421 | 1.00 | RIPK1 (0.34) | RIPK1ABCB1F2ELANECTSG | |
| SCHEMBL1728236 | 1.00 | RIPK1 (0.34) | RIPK1ABCB1F2ELANECTSG | |
| SCHEMBL6063849 | 0.83 | ABCB1 (0.44) | RIPK1ABCB1F2ELANECTSG | |
| SCHEMBL18109310 | 0.75 | ABCB1 (0.43) | RIPK1ABCB1F2ELANECTSG | |
| SCHEMBL19461110 | 0.75 | ABCB1 (0.43) | RIPK1ABCB1F2ELANECTSG | |
| SCHEMBL18109311 | 0.75 | ABCB1 (0.43) | RIPK1ABCB1F2ELANECTSG | |
| SCHEMBL6063753 | 0.75 | ELANE (0.36) | RIPK1F2ELANECTSGALDH1A1 | |
| SCHEMBL6063582 | 0.75 | ELANE (0.36) | RIPK1F2ELANECTSGALDH1A1 | |
| SCHEMBL8295855 | 0.73 | ABCB1 (0.44) | RIPK1ABCB1F2ELANECTSG | |
| SCHEMBL1729949 | 0.71 | USP2 (0.37) | RIPK1ABCB1ELANEALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651653-B1 | NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-11-23 | — | — | EP | disclosed |
| EP-1651653-A1 | NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | Sanofi-Aventis Deutschland GmbH (DE) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012312-A1 | NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-02-10 | — | — | WO | disclosed |