Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894291 | 0.81 | NR1H2 (0.42) | USP2TSHRABCB1RORCKMT2A | |
| SCHEMBL894292 | 0.81 | NR1H2 (0.42) | USP2TSHRABCB1RORCKMT2A | |
| SCHEMBL3706217 | 0.81 | NR1H2 (0.42) | USP2TSHRABCB1RORCKMT2A | |
| SCHEMBL10207129 | 0.72 | POLB (0.49) | USP2TSHRABCB1GAAALDH1A1 | |
| SCHEMBL7900809 | 0.71 | GAA (0.40) | USP2TSHRGAAALDH1A1CYP2C9 | |
| SCHEMBL9235945 | 0.71 | GAA (0.40) | USP2TSHRGAAALDH1A1CYP2C9 | |
| SCHEMBL6822684 | 0.71 | GAA (0.40) | USP2TSHRGAAALDH1A1CYP2C9 | |
| SCHEMBL3728141 | 0.71 | GAA (0.40) | USP2TSHRGAAALDH1A1CYP2C9 | |
| SCHEMBL1728421 | 0.71 | RIPK1 (0.34) | TSHRABCB1GAAALDH1A1RIPK1 | |
| SCHEMBL1728236 | 0.71 | RIPK1 (0.34) | TSHRABCB1GAAALDH1A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651653-B1 | NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-11-23 | — | — | EP | disclosed |