SCHEMBL17284073

SCHEMBL17284073

COc1cc(N=Nc2c(S(=O)(=O)O)cc3cc(Nc4ccccc4)ccc3c2O)c(OC)cc1N=Nc1cc(C)c(N=Nc2ccc(N=Nc3cc4c(S(=O)(=O)O)cc(S(=O)(=O)O)cc4cc3S(=O)(=O)O)c(C)c2)cc1C

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 11/20 0.74
CD40 P25942 1/20 0.49
CD40LG P29965 1/20 0.49
PHLPP2 Q6ZVD8 3/20 0.46
PRMT3 O60678 1/20 0.45
EP300 Q09472 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
PRMT1 Q99873 1/20 0.45
ALDH1A1 P00352 1/20 0.44
HIF1A Q16665 1/20 0.44
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17460961 1.00 ENPP2 (0.74) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL19235098 0.99 ENPP2 (0.72) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL17283952 0.96 ENPP2 (0.81) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL14773714 0.96 ENPP2 (0.81) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL19234841 0.96 ENPP2 (0.81) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL19958178 0.96 ENPP2 (0.81) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL18910730 0.96 ENPP2 (0.81) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL19235099 0.95 ENPP2 (0.73) ENPP2CD40CD40LGPHLPP2PRMT3
SCHEMBL17284053 0.94 ENPP2 (0.66) ENPP2CD40CD40LGPHLPP2PRMT1
SCHEMBL15935775 0.94 ENPP2 (0.66) ENPP2CD40CD40LGPHLPP2PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 ENPP2 2889/4885CD40 4579/4885CD40LG 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.