SCHEMBL1728419

SCHEMBL1728419

FCC(CF)(CF)c1c[c]ccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1420030 0.81 ALDH1A1 (0.31)
SCHEMBL3600103 0.79 TAAR1 (0.33)
SCHEMBL3371 0.75 TSHR (0.48)
Water SCHEMBL27821326 0.75 TSHR (0.48)
SCHEMBL17134201 0.74
SCHEMBL3891340 0.73 TSHR (0.46)
SCHEMBL20526431 0.73 TSHR (0.46)
SCHEMBL28824905 0.73 TSHR (0.46)
Benzene SCHEMBL8005754 0.73 TSHR (0.52)
SCHEMBL3889885 0.73 TSHR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673337-B1 Arylalkylcarbamate derivatives, preparation method thereof and use of same in therapeutics SANOFI SA (FR) 2011-11-23 EP disclosed