Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172475 | 0.83 | LMNA (0.71) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9355358 | 0.82 | LMNA (0.69) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9348416 | 0.74 | LMNA (0.50) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL18562228 | 0.74 | CDK2 (0.47) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9178476 | 0.73 | LMNA (0.73) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10488023 | 0.72 | CDK2 (0.59) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10488101 | 0.72 | CDK2 (0.59) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL18991906 | 0.72 | LMNA (0.61) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10488008 | 0.72 | LMNA (0.54) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8605499 | 0.70 | LMNA (0.65) | LMNAMAPTALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385215-B2 | Polymerizable dichroic dyes | ROLIC AG (CH) | 2019-08-20 | — | — | US | disclosed |
| US-20170058126-A1 | POLYMERIZABLE DICHROIC DYES | ROLIC AG (CH) | 2017-03-02 | — | — | US | disclosed |
| US-20170058126-A1 | POLYMERIZABLE DICHROIC DYES | ROLIC AG (CH) | 2017-03-02 | — | — | US | disclosed |
| WO-2015177062-A1 | POLYMERIZABLE DICHROIC DYES | ROLIC AG (CH) | 2015-11-26 | — | — | WO | disclosed |