SCHEMBL9355358

SCHEMBL9355358

Cc1ccc(S(=O)(=O)Nc2cccc3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.69
MAPT P10636 6/20 0.69
ALDH1A1 P00352 4/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
CYP2C9 P11712 2/20 0.69
CYP2C19 P33261 2/20 0.69
USP2 O75604 1/20 0.69
POLB P06746 1/20 0.69
NOD2 Q9HC29 1/20 0.69
KMT2A Q03164 4/20 0.67
MEN1 O00255 3/20 0.67
SMN1; SMN2 Q16637 3/20 0.67
KDM4E B2RXH2 1/20 0.67
PGAM1 P18669 2/20 0.66
CA2 P00918 3/20 0.62
CA9 Q16790 3/20 0.62
CA12 O43570 2/20 0.62
MCOLN3 Q8TDD5 1/20 0.62
HTT P42858 3/20 0.61
CDK2 P24941 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172475 0.95 LMNA (0.71) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL9178476 0.91 LMNA (0.73) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL8605499 0.88 LMNA (0.65) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL9171170 0.83 PGAM1 (0.67) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL9846547 0.83 CDK2 (0.62) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL9355616 0.83 LMNA (0.61) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL17284258 0.82 LMNA (0.53) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL9445876 0.81 PGAM1 (0.68) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL2068526 0.81 LMNA (0.82) LMNAMAPTALDH1A1L3MBTL1CYP2C9
SCHEMBL10488023 0.80 CDK2 (0.59) LMNAMAPTALDH1A1L3MBTL1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368750-B1 Process for preparing substituted aminoanthraquinones SUMITOMO CHEMICAL CO (JP) 1994-10-26 EP disclosed
US-5017713-A Alkylation SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1991-05-21 US disclosed
EP-0368750-A2 Process for preparing substituted aminoanthraquinones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed
EP-0008063-B1 AZOMETHINE DERIVATIVES OF ANTHRAQUINONES, METHODS FOR THEIR PREPARATION, THEIR USE IN THE PIGMENTATION OF ORGANIC MACROMOLECULAR COMPOUNDS AND THE MATERIALS THUS OBTAINED BAYER AG (DE) 1982-06-09 EP disclosed