SCHEMBL1728504

SCHEMBL1728504

Oc1ccccc1C1OO1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
ALOX15 P16050 4/20 0.45
MAPT P10636 3/20 0.45
RAB9A P51151 3/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 2/20 0.45
NPC1 O15118 2/20 0.45
POLB P06746 2/20 0.45
EGFR P00533 2/20 0.45
CA2 P00918 2/20 0.45
LMNA P02545 2/20 0.45
FYN P06241 2/20 0.45
MMP9 P14780 2/20 0.45
RECQL P46063 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CA12 O43570 1/20 0.45
GMNN O75496 1/20 0.45
CA3 P07451 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2048903 0.78 HTR2A (0.44) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL27593793 0.78 AR (0.46) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL30118303 0.77 AR (0.41) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL11132969 0.77 HTR2A (0.39) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL31169126 0.76 ALDH1A1 (0.47) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL9946123 0.75 MEN1 (0.42) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL1374931 0.75 MEN1 (0.43) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL9826763 0.75 HTR2A (0.42) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL3957434 0.72 AR (0.41) ALDH1A1ALOX15MAPTRAB9AHPGD
SCHEMBL7263200 0.72 HTR2A (0.47) ALDH1A1ALOX15MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1378348-B1 Thermosensitive lithographic printing plate FUJIFILM CORP (JP) 2011-11-23 EP disclosed
EP-0195493-B1 TRANSPARENT ARTICLE AND PROCESS FOR PREPARATION THEREOF TORAY INDUSTRIES, INC. (JP) 1993-03-24 EP disclosed
US-4895767-A EPOXY RESIN, SILICON COMPOUND TORAY INDUSTRIES, INC. (JP) 1990-01-23 US disclosed
EP-0195493-A2 Transparent article and process for preparation thereof TORAY INDUSTRIES, INC. (JP) 1986-09-24 EP disclosed