SCHEMBL2048903

SCHEMBL2048903

Oc1ccccc1C1OCCO1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 4/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 2/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HPGD P15428 2/20 0.39
ALOX15 P16050 2/20 0.39
RAB9A P51151 2/20 0.39
HSD17B10 Q99714 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP3A4 P08684 2/20 0.39
CA12 O43570 1/20 0.39
GMNN O75496 1/20 0.39
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1374931 0.91 MEN1 (0.43) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL27820532 0.84 TERT (0.40) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL3727526 0.83 TSHR (0.36) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL9826763 0.83 HTR2A (0.42) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL6132290 0.81 KMT2A (0.53) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL7863220 0.79 CHRNB2 (0.33) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL3957434 0.79 AR (0.41) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL1728504 0.78 ALDH1A1 (0.45) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL30317690 0.76 AR (0.45) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL16060505 0.74 MMP2 (0.38) MEN1KMT2AMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015051525-A1 SYNTHESIS OF ACETAL/KETAL RHODIA OPERATIONS (FR) 2015-04-16 WO claimed
EP-0301638-B1 Improved process for producing n-alkyl-carbamates ENICHEM SINTESI (IT) 1993-12-08 EP claimed
EP-0446514-B1 PROCESS FOR THE PREPARATION OF ARYL ESTERS OF N-ALKYL CARBAMIC ACIDS Council of Scientific and Industrial Research (IN) 1993-03-10 EP claimed
US-5066819-A Process for the preparation of aryl esters of N-alkyl carbamic acids COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1991-11-19 US claimed
EP-0446514-A1 Process for the preparation of aryl esters of N-alkyl carbamic acids Council of Scientific and Industrial Research (IN) 1991-09-18 EP claimed
US-5021590-A Reacting alkyl isocyanates with phenols in solution using bicyclic amidine or guanidine catalyst ENICHEM SYNTHESIS SPA (IT) 1991-06-04 US claimed
EP-0190466-B1 PROCESS FOR THE PRODUCTION OF N-METHYLCARBAMATES ENICHEM SYNTHESIS S.p.A. (IT) 1990-11-28 EP claimed
CN-1004353-B Process for preparing N-methyl carbamates 埃尼凯姆·辛泰希公司 1989-05-31 CN claimed
EP-0301638-A2 Improved process for producing n-alkyl-carbamates ENICHEM SYNTHESIS S.p.A. (IT) 1989-02-01 EP claimed
CN-85109417-A The preparation method of N-methyl carbamate class 1986-12-03 CN claimed
EP-0190466-A1 Process for the production of N-Methylcarbamates ENICHEM SYNTHESIS S.p.A. (IT) 1986-08-13 EP claimed
US-4315861-A Process for O-acylating phenol derivatives and acylating compositions for this purpose Chinoin Gyogyszer RT (HU) 1982-02-16 US claimed
US-4113876-A INSECTICIDES, FUNGICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-12 US claimed
JP-3200784-A None JP disclosed
US-9580379-B2 Xanthine oxidase inhibitors and methods of use BAYLOR COLLEGE OF MEDICINE (US) 2017-02-28 US disclosed
US-9580379-B2 Xanthine oxidase inhibitors and methods of use BAYLOR COLLEGE OF MEDICINE (US) 2017-02-28 US disclosed
US-4086246-A REACTION OF PHOSGENE WITH A PHENOL AND PRIMARY AMINE CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA (HU) 1978-04-25 US disclosed
US-4006244-A INSECTICIDE, FUNGICIDE, BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed
US-3944674-A Combating insects with o dimethoxymethylphenyl-N-methylcarbamate CIBA-GEIGY AG (CH) 1976-03-16 US disclosed
US-3933858-A INSECTICIDES CIBA-GEIGY AG (CH) 1976-01-20 US disclosed