Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | DBH | P09172 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013672 | 0.79 | GRM1 (0.41) | GRM1FFAR4L3MBTL1LMNAMAPT | |
| SCHEMBL10400222 | 0.70 | BIRC5 (0.47) | GRM1FFAR4TUBB1L3MBTL1CYP1A2 | |
| SCHEMBL4140155 | 0.70 | TUBB1 (0.62) | TUBB1TRPA1LMNANFE2L2MAPK1 | |
| SCHEMBL1014388 | 0.69 | GRM1 (0.43) | GRM1FFAR4TUBB1L3MBTL1LMNA | |
| SCHEMBL14085797 | 0.68 | TRPA1 (0.43) | TRPA1L3MBTL1MAPTMAPK1 | |
| SCHEMBL7264816 | 0.67 | EGFR (0.38) | GRM1FFAR4TUBB1L3MBTL1LMNA | |
| SCHEMBL1122795 | 0.66 | BRD4 (0.46) | GRM1MAPK1F10 | |
| SCHEMBL1687375 | 0.63 | TRPA1 (0.61) | TUBB1TRPA1L3MBTL1MAPTNFE2L2 | |
| SCHEMBL23883999 | 0.62 | FFAR4 (0.52) | FFAR4LMNAMAPTCYP1A2RAB9A | |
| SCHEMBL30234615 | 0.62 | FFAR4 (0.52) | FFAR4LMNAMAPTCYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009617-A3 | METHODS, STORAGE MEDIUMS, AND SYSTEMS FOR ANALYZING PARTICLE QUANTITY AND DISTRIBUTION WITHIN AN IMAGING REGION OF AN ASSAY ANALYSIS SYSTEM AND FOR EVALUATING THE PERFORMANCE OF A FOCUSING ROUTING PERFORMED ON AN ASSAY ANALYSIS SYSTEM | LUMINEX CORPORATION (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2271617-B1 | SUBSTITUTED 4-HYDROXY-N- (4-HYDROXYPHENYL) INDOLES AS ESTROGENIC AGENTS | GLAXO GROUP LTD (GB) | 2011-11-30 | — | — | EP | disclosed |
| US-7956083-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2011-06-07 | — | — | US | disclosed |
| US-7956083-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2011-06-07 | — | — | US | disclosed |
| US-7956083-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2011-06-07 | — | — | US | disclosed |
| US-20100324106-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | US | disclosed |
| WO-2009103710-A1 | SUBSTITUTED 4-HYDROXY-N- (4-HYDROXYPHENYL) INDOLES AS ESTROGENIC AGENTS | GLAXO GROUP LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324106-A1 | COMPOUNDS | ESR2, GPER1, ESR1 | GRM1 425/4885FFAR4 244/4885TUBB1 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.