Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18212070 | 0.92 | NPC1 (0.41) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL23155228 | 0.92 | NPC1 (0.35) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL25608187 | 0.91 | NPC1 (0.40) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL17083563 | 0.91 | MAPT (0.40) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL21140999 | 0.90 | NPC1 (0.38) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL17734638 | 0.89 | MAOA (0.36) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL18212124 | 0.88 | PLA2G2A (0.42) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL26687150 | 0.88 | NPC1 (0.35) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL19885485 | 0.88 | PLA2G2A (0.36) | HPGDMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL27111889 | 0.87 | AHR (0.43) | HPGDMAPTNPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150340636-A1 | Electronic Device | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |