Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.67 |
| ▸ | DRD3 | P35462 | 7/20 | 0.67 |
| ▸ | HTR1A | P08908 | 6/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.67 |
| ▸ | HTR2C | P28335 | 3/20 | 0.67 |
| ▸ | DRD4 | P21917 | 3/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727824 | 0.92 | DRD3 (0.75) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL1728118 | 0.85 | DRD3 (0.59) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL23751044 | 0.82 | MEN1 (0.62) | DRD4FAAH | |
| SCHEMBL4513849 | 0.81 | DRD3 (1.00) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL239772 | 0.80 | DRD4 (0.58) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL3664190 | 0.79 | DRD2 (0.59) | DRD2DRD3HTR1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL237609 | 0.79 | DRD4 (0.57) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL9283836 | 0.79 | DRD2 (0.59) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL23750995 | 0.79 | HSD17B10 (0.64) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL13711982 | 0.77 | DRD3 (0.60) | DRD2DRD3HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | disclosed |
| CN-1812980-B | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their use as pharmaceuticals | SANOFI AVENTIS | 2011-04-06 | — | — | CN | disclosed |
| CN-101712660-A | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their therapeutic use | SANOFI AVENTIS | 2010-05-26 | — | — | CN | disclosed |
| CN-1812980-A | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2006-08-02 | — | — | CN | disclosed |
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |